Atherosclerotic Coronary Vulnerable Plaque: Correlation With Coronary Artery Calcium

Inclusion Criteria

• •Patient is ≥18 years of age
• •Patient is clinically indicated due to angina, abnormal functional test or other ischemic symptoms to undergo non-emergent cardiac catheterization with IVUS evaluation i.If the patient has not had a cardiac MDCT with CACS meeting the protocol requirements within 3 months prior to the cardiac catheterization, the patient is able to undergo CACS following LipiScan IVUS and NIRS evaluation, prior to any coronary revascularization ii. If the patient has had a cardiac MDCT evaluation with CACS meeting the protocol requirements within 3 months prior to the cardiac catheterization, LipiScan IVUS and NIRS imaging will be completed in at least two (2) major epicardial vessels prior to any coronary revascularization
• •At least two (2) major epicardial native vessels are suitable for interrogation by LipiScan IVUS imaging and NIRS evaluation, defined as:
• •i.At least 30 mm of vessel that is \> 2.0mm in diameter ii.No other contraindications to imaging
• •No contraindications for LipiScan IVUS and NIRS evaluation
• •No contraindications for CACS evaluation by MDCT
• •Subject must be able to provide informed consent form and comply with the protocol requirements