Pioglitazone Decreases Visceral Fat Metabolism

Exclusion Criteria

• •Subjects with insulin treatment
• •Subjects with uncontrolled diabetes, hypertension, symptomatic coronary artery disease, symptomatic cerebrovascular disease
• •Subjects taking more than three antidiabetic medications
• •Subjects taking anti-platelet, statins, antidiabetic agents, thiazolidinediones within 8 weeks prior to randomization
• •Subjects with cardiac failure (New York Heart Association Class \> III) or left ventricular dysfunction (LVEF \< 40%)
• •Subjects with systemic disorders such as active inflammatory, liver, renal, hematopoietic, and malignant disease