severe daytime sleepiness (Epworth rating scale \> 15)
known cardiovascular pathologies
contraindication to CPAP
allergy to nebivolol
patient treated with antihypertensive drug(s), with class I antiarrhythmics (quinidine, hydroquinidine, cibenzoline, flecainide, disopyramide, lidocaine, mexiletine, propafenone)
patient treated with CPAP
patient kept in detention, major protected by the law, hospitalised person
patient currently participating in another clinical trial
