Glucocorticoids in Patients With IgG4-RD

Inclusion Criteria

• •Males and females
• •Age 18-70 years old with informed consent
• •Patients with IgG4-RD:
• •1. swelling, sclerosing and inflammatory involvement of one or more organ, including sclerosing pancreatitis, sclerosing cholangitis, inflammatory pseudotumors, retroperitoneal or mediastinal fibrosis, interstitial nephritis, hypophysitis, sclerosing dacryoadenitis, sialadenitis, inflammatory aortic aneurysm, lymphadenopathy, or other inflammatory conditions;
• •2. elevated serum IgG4 (\>1.35 g/L)
• •3. histopathologic features of fibrosis and/or lymphocytic and polyclonal plasma cell infiltration (and IgG4+ plasma cells on immunohistology when performed);
• •4. exclusion of other diseases.