Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Brown, Theodore R., M.D., MPH
With
Biogen
Purpose of this study is to assess the intra-rater and inter-rater reliability of a hand-held dynamometer (HHD) in the assessment of lower limb strength in patients with Multiple Sclerosis.
Also to establish a standardized strength testing procedure for key lower limb muscle groups using a HHD fo research and clinical purposes in Multiple Sclerosis.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Stable patients with clinically definite Multiple Sclerosis
No Multiple Sclerosis exacerbation 30 days prior to screening
No change in disease modifying therapy for 30 day prior to screening
You may not be if
Inflammatory myopathy
Endocarditis, pericarditis o rother unstable heart disease
Cardiac surgery or myocardial infarction in the last 3 months
Decompensated congestive heart failure
Severe aortic stenosis
Severe pulmonary hypertension
Pulmonary embolus or infarction in the last 6 months
Uncontrolled hypertension by history or by screening or baseline diastolic blood pressure \>170 or systolic blood pressure \>105
Concomitant neurodegenerative neurological disease such as Amyotrophic Lateral Sclerosis (ALS) Parkinsons or hemiplegic stroke
females who are pregnant
Cognitive deficits that would interfere with the subjects's ability to give informed consent or preform study testing
Painful orthopedic condition affecting the lower limbs
Any other serious and/or unstable medical condition
