Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer

Background: When substituting a random biopsy procedure with a few targeted biopsies, it is of outmost importance to know immediately if the biopsy is positive or not. A recent study has demonstrated a high sensitivity and specificity of imprint cytology of random biopsies. Aim: The correlation between cytological imprints and histology of targeted prostate biopsies Material\&Method: All patients in this study are already participating in an ongoing randomized biopsy study (NCT01455792) comparing: 1. Preoperative MRI and targeted biopsies + random biopsies . 2. Random biopsies (gold standard). Only patients with a positive MRI were included in this collateral study. The cytological imprints (negative/positive) of each targeted biopsy is compared to the histology (negative/positive) and Gleason score.