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Off Clamp Randomization | Clinical Trials | Clareo Health

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COMPLETEDNANCT01732120

Off Clamp Randomization

The purpose of this research study is to compare the effects on kidney function after performing the removal of a kidney tumor with or without clamping the blood vessels during surgery.

Lead sponsor: Washington University School of Medicine•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Washington University School of Medicine

Collaborators

Midwest Stone Institute.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients 18 and older.
•Patients willing and able to sign consent.
•Patients with an organ confined renal mass planning to undergo a robotic assisted partial nephrectomy (RAPN).
•Patient with Karnofsky Performance Status (KPS) equal to or greater than 40.

Exclusion Criteria

•Patients under 18.
•Patients with Karnofsky Performance Status (KPS) less than 40.
•Patients with non-organ confined renal masses (invading renal vein, inferior vena cava, peri-renal tissue, ipsilateral adrenal gland, or metastasis).
•Patients with bilateral synchronous renal masses.
•Patients who can not discontinue Plavix, Coumadin or other anti-platelet or anti-coagulant medications.
•Patients with renal lesions determined to be too complex to perform a RAPN without clamp by the surgeon. (The renal mass may be deemed too difficult based on pre-operatively radiological findings. The surgeon's decision to exclude a mass from a robotic assisted partial nephrectomy would be based on a higher risk of positive margin or complication if a RAPN was performed.)

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 19, 2023Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment80

Start dateNov 2012

Last updatedMay 19, 2023

Condition

Renal Cancer Renal Ischemia

Locations shown

Washington University School of Medicine

St Louis, Missouri

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 19, 2023Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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