A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD)

Exclusion Criteria

• •Histologic evidence of cirrhosis
• •Any co-existent liver disease
• •A platelet count \< 90,000
• •A total white blood cell (WBC) \< 2.5
• •An absolute neutrophil count \< 1.5
• •Hemoglobin \< 11 gm/dl on Epoetin-alpha
• •Positive test for anti-HIV
• •Pregnancy of the patient or their intimate partner
• •Women who are breast feeding
• •Significant cardiovascular disease
• •History of suicide intent, severe depression requiring hospitalization or significant psychiatric disease
• •Malignancy within 5 years of enrollment except for squamous or basal cell skin cancer
• •Co-existent immune disorder such as lupus, rheumatoid as arthritis, colitis, Crohns disease, sarcoidosis, etc.
• •Any patient in the opinion of the investigator who would not be a satisfactory study candidate