Compliance/Adherence After Kidney Transplant, With or With Out Med-O-Wheel™.

Study objectives: To investigate whether Med-O-Wheel™ can improve - 1. adherence to medication regimens, 2. adherence to appointments at the outpatient clinic, and 3. treatment outcome in renal transplant patients. Methodology Study design: Open, prospective, descriptive, randomized study. Primary research question: Can Med-O-Wheel™ improve adherence to the prescribed medication regimen in renal transplant patients? Efficacy parameters: P-Creatinine, concentrations of medication (B-tacrolimus, B-cyclosporine, B-sirolimus, P/S-mycophenolate, B-TPMT-metabolites) and age(years). Addoz Portal for Med-O-Wheel™. Study-specific questionnaire to survey patient discomfort relating to compliance and adherence. Safety parameters: Med-O-Wheel™ and Addoz Portal™ is a CE-approved product with a guarantee for continuous operation. Karolinska University Laboratory is an accredited testing laboratory. Volunteer population Subjects: All patients about to undergo renal transplantation at Karolinska University Hospital. Number: 80 patients (40 patients with Med-O-Wheel™, 40 patients with out Med-O-Wheel™). Time frame First patient included: Juni 2011. Last patient included: Juli 2012. Last patient completed: Juli 2013.