autoimmune disorders, concomitant use of immunosuppressive drugs
serious concomitant disease, serious active infections, other malignancy in the past 5 years with the exception of curatively treated carcinoma in-situ of the cervix/squamous cell carcinoma of the skin
known allergy to shell fish (vaccine contains KLH)
pregnancy or lactation
clinical signs of CNS metastases, in patients with a clinical suspicion of CNS metastases, a CT scan of the brain should be performed to exclude this
prior chemotherapy, immunotherapy, or radiotherapy within three months before planned vaccination is allowed
