Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Colorado, Denver
With
Colorado Clinical & Translational Sciences Institute
Age
5–35
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 5 years and ≤ 35 years
Receiving influenza vaccination in Children's Hospital Colorado (CHC) clinic as part of routine clinical care
Only supposed to receive one dose of influenza vaccine
Rheumatology patients: must be on some type of immunosuppressive or immunomodulatory medication at the time of immunization and considered at least moderately immunosuppressed in the opinion of the primary rheumatologist. Basic guidelines for rheumatology patients: (1) Any patient receiving monoclonal antibody therapy (i.e., infliximab, etanercept, tocilizumab, anakinra) must also be taking another immunosuppressive/immunomodulatory medication; (2) Patients taking steroids as monotherapy must be on a dose of ≥ 2mg/kg/day OR ≥ 20mg/day; (3) Patients on combination therapy where the dose of a single drug may not be very high, but the combination is considered moderately or severely immunosuppressive will be eligible.
Bone Marrow Transplant patients: all patients in clinic eligible
Oncology patients: must be on some type of chemotherapy
Hemodialysis patients: must be on dialysis
Child Health Immunodeficiency Program (CHIP) patients: must have a known diagnosis of HIV
Solid Organ Transplant patients: post-transplant, influenza vaccine recommended by primary transplant physician
You may not be if
Rheumatology patients: if receiving any of the monoclonal antibodies, etanercept, infliximab, adalimumab, tocilizumab, atlizumab, or anakinra, must also be taking at least one other immunosuppressive/immunomodulatory medication
Unable to come for scheduled follow-up appointments
History of anaphylaxis reaction to influenza vaccination in the past
Severe allergic reaction to any component of the vaccine, including egg protein, or after previous dose of any influenza vaccine
History of Guillain-Barre syndrome ever in the past in the subject or in a parent or a sibling of the subject
Allergy to latex
Intravenous immuneglobulin (IVIG) within in 4 weeks preceding any blood draw
Receiving an investigational agent as part of another study or other medical treatment (investigational = not-FDA approved for any indication)
Subject not enrolled in other studies that prohibit him/her from enrolling in this study
Blood draw contraindicated
Pregnancy
Breastfeeding
Received a polysaccharide vaccine (pneumovax) w/in 3 weeks of the vaccination
Absolute neutrophil count (ANC) \< 500/uL at the time of vaccination or could potentially have ANC 500/uL during the 5 days after vaccination
Platelet count \< 50,000/uL at the time of vaccination
If a subject has a temperature ≥ 100.4°F at the time of enrollment, then the subject must choose to not enroll or delay immunization until afebrile.
Receiving influenza vaccination past December 15 of influenza season.
Clareo Health | Immunogenicity of Fluzone High Dose in Immunocompromised Children and Young Adults
