Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University Hospital of North Norway
With
University of Tromso
The Royal Norwegian Ministry of Health
Odd Berg Medical research Foundation
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 18 Years.
Resistant hypertension, as defined in the 2007 ESH-ESC guidelines and confirmed by ambulatory or home blood pressure measurements. (Here office BP \> 140/90 mmHg on 4 or more antihypertensive drugs in adequate dosages (including one diuretic) or certified drug intolerance).
No known secondary reason for hypertension
Negative pregnancy test (preferably blood hCG) for female patients of childbearing potential
Estimated GFR (glomerular filtration rate) \> 45 mL/min/1.73m².
Willing and able to comply with follow-up requirements
Signed informed consent
You may not be if
Type 1 and type 2 diabetes
Pregnancy
Allergy to the contrast medium used during RDN and Iohexol clearance.
Age \> 68 years
Hemodynamically significant heart valve disease
Pacemaker or ICD
Medication that may interfere with the procedure (Anticoagulation, Platelet inhibitors, Steroids), if they cannot be temporarily reduced or stopped.
Cancer
Patients with transplanted kidneys
Reno vascular conditions like diameter \< 4mm, renal artery stenosis or significant atherosclerosis, previous renal artery stenting
Clareo Health | Renal Sympathetic Denervation and Potential Effects on Glucose Metabolism and Cardiovascular Risk-Factors