All antihypertensive agents were withdrawn before the start of a 4-6 week, single-blind, after which the patients received candesartan 10 mg or 20mg once daily as monotherapy in a single-blind fashion. The doses were doubled after 1 weeks if DBP was ≥ 90 mmHg.
Age
30–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
men and women with mild to moderate essential hypertension in southwestern Han Chinese
You may not be if
subjects unwilling to participate or subjects did not have all measurement required,
subjects who were on medications, which affect blood pressure or
whose DNA failed to amplify and 8 with errors in Mendelian segregation
