Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment

Exclusion Criteria

• •Patients with blood pressure ≥ 180/100 mmHg;
• •Patients with uncontrolled hypertension (≥ 140/90 mmHg) treated with thiazide diuretics;
• •Presence of concomitant coronary artery disease, congestive heart failure, diabetes and renal failure (creatinine\> 1.5 mg / dL);
• •Patients with hypo or hyperkalemia (serum potassium outside normal range);
• •Patients with ALT greater than 2.5 the upper limit of normal or active liver disease;
• •Pregnant women, or women in childbearing age who are not in use effective contraception or intending to become pregnant during the study period;
• •Patients on drug or alcohol abuse in the last two years;
• •Patients with secondary hypertension (renovascular disease, pheochromocytoma, Cushing's syndrome);
• •Patients with allergic reactions or hypersensitivity to ACE inhibitors, diuretics or medications containing sulfa and / or any excipients of formulation;
• •Refusal or inability to provide the Informed Consent Term.;
• •Refusal to discontinue the anti-hypertensive medication.
• •Patients at the discretion of the investigator does not have indication for discontinuing the current medications;