About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNANCT01612130

Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery

The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surg...

Lead sponsor: Federal University of the Valleys of Jequitinhonha and Mucuri•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Federal University of the Valleys of Jequitinhonha and Mucuri

Collaborators

University of Campinas, Brazil

Evaluate the efficacy of Valeriana officinalis L. (Valerian) for control of anxiety during third molar surgery. Study design: A single oral dose of either valerian (100 mg) or placebo was randomly administered one hour before each surgical procedure to 20 volunteers between 17 and 31 years of age. Anxiety level was assessed through questionnaires, physiological parameters (blood pressure and heart rate) and the observation of signs.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Indication for bilateral extraction of asymptomatic impacted mandibular third molars in similar positions based on the Pell \& Gregory classification

Exclusion Criteria

•Use of any type of medication in the 15 days prior to the onset of the study; history of hypersensitivity to the drugs, substances or materials employed in the experiment; pregnancy or lactation

Related studies

RECRUITINGPhase 2/3

PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

NCT04971720 · Obesity, Cardiovascular Diseases, and more

Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment

NCT07396636 · Intraoperative Hypotension, Perioperative Care, and more

The Venous Distension Reflex and Orthostatic Hypertension

NCT03496792 · Blood Pressure

Use of Augmented Reality Glasses and Noise-Cancelling Headphones to Reduce Dental Anxiety in Adult Patients

NCT07398898 · Dental Anxiety, Music Therapy, and more

Transcutaneous Auricular Vagus Nerve Stimulation and Spirometry: Sham-Controlled Randomized Trial

NCT07482930 · Vagus Nerve Stimulations, Spirometry, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 6, 2012Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment20

Start dateMar 2003

Last updatedJun 6, 2012

Condition

Dental Anxiety Blood Pressure Heart Rate

Locations shown

Oral-Maxillofacial Surgery Sector of the Piracicaba Dental School, Universidade Estadual de Campinas (Brazil)

Piracicaba, São Paulo

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 6, 2012Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions