Study of Stress and Life Quality of Patients Participating in Clinical Trials Versus Patients Non Participating

Inclusion Criteria

• •patient with solid tumor or recurrent hematologic cancer, treated by chemotherapy or targeted therapy evaluated every 2 or 3 cycles; except for clinical trials associating non drug treatment (radiotherapy, surgery...)
• •subject to a 1st, 2nd or 3rd line of antitumor treatment
• •* a phase 2 open labeled study,
• •* a phase 2 or 3 blind randomised study,
• •* a phase 2 or 3 open randomised study,
• •* a standard treatment non participating to a clinical trial
• •male or female patients ≥ 18 years of age
• •karnovsky ≥ 70 % or WHO (Performance Status) ≤ 2
• •recovered from prior toxicities
• •social security covered
• •written informed consent given