Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
GWT-TUD GmbH
August-1 is a register to find out to which extent RCT patients are representative for the overall patient collective with dfs and critical limb ischemia and to evaluate the therapeutic success of other treatment strategies. An RCT to assess the efficacy of urokinase versus placebo is imbedded in the register.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
diabetic patients with dfs and critical limb ischemia
age 18 and older
You may not be if
less than 1 year life expectancy
prior major amputation
planned major expectation
prior treatment of the current episode of dfs with urokinase
mechanical heart valve replacement
cerebral event with changes in CT during the last three months
hemorrhagic diathesis (spontaneous quick value \< 50%, spontaneous ptt \> 40 sec, thrombocytes \< 100 gpt/l)
acute gastrointestinal bleeding or ulcers during the last 4 weeks
prior reverse bypass operation
concomitant participation in other clinical trials
insufficient compliance
premenopausal women not using a safe method of contraception (i. e. IUD, hormone implants, hormone depot injection, combined pill (estrogens and gestagens), vaginal ring or vasectomized partner).
