Investigation on the Middle Size Molecule Elimination Characteristics of the FXCorDiax 100 in Relation to the FX 100 and the Polyflux 210 H Dialyser

Inclusion Criteria

• •hemodialysis patients 18 years and older
• •treated by post dilution on-line Hemodiafiltration (HDF) for at least one month
• •who reached a dialysis dose (Kt/V) of at least 1.2 at each of the last two monthly checks
• •who are on a stable anticoagulation and anemia management
• •whose hemoglobin is between 10.5 and 13.0 g/dl
• •who are clinically stable based on judgment of nephrologist
• •who are on a regular thrice weekly HDF schedule, e.g. Monday-Wednesday-Friday or Tuesday-Thursday-Saturday,
• •who have a good vascular access (fistula or graft) which enables easy insertion of the needles and suitable effective blood flow (\> 300 ml/min)
• •who are able to understand the nature and requirements of the clinical investigation and who have given written informed consent