Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Wageningen University
With
Top Institute Food and Nutrition
This is a randomized, double-blind, placebo controlled cross-over feeding study.
Age
40–90
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
(Pre)hypertension, defined as office SBP: 130-159 mmHg;
No use of antihypertensive, lipid-lowering, anticoagulant or other cardiovascular medication;
Age at start of the ≥ 40 years;
Apparently healthy:
* No reported current or previous metabolic diseases
* No history of cardiovascular diseases
* No history of renal, liver or thyroid diseases
* No history of gastrointestinal diseases
* No diabetes mellitus
* Fasting laboratory parameters within normal range: renal function (serum creatinine, ureum), liver function (ALAT, ASAT, ɣ-GT) and serum glucose.
You may not be if
Body mass index \> 40 kg/m²;
Smoking
Secondary hypertension;
Weight loss or weight gain of 5 kg or more during the last 2 months;
Usage of non-steroidal anti-inflammatory drugs (aspirin, ibuprofen, naproxen) and not able or willing to stop taking them from at least 4 weeks prior to the study.
Medical treatment that may affect blood pressure and not able (or willing) to stop taking them;
Women taking oral contraceptives or estrogen replacement therapy
Taking nutritional supplements and unwilling to discontinue;
Women lactating, pregnant or intend to become pregnant during study;
