Clareo Health | A Study of Continuous Endostar Intravenous Infusion Combined With Pemetrexed and Carboplatin in Advanced Non Small Cell Lung Cancer Patients
With uncontrollable malignant pleural effusion or ascites
Thoracic or abdominal surgery within 28 days prior to study entry
History of cerebral stroke or TIA within 6 months prior to study entry
With uncontrollable hypertension, hypertensive emergency or hypertensive encephalopathy
Arrhythmia in need of antiarrhythmic treatment, history of angina pectoris, myocardial infarction, myocardial ischemia or congestive heart failure (\> NYHA class II)
With serious infection (\> NCI CTC grade 2)
Gastrointestinal perforation, fistula formation, and/or intra-abdominal abscess within 6 months prior to study entry
Symptomatic brain metastases
Patient who has epilepsy
History of HIV infection or chronic hepatitis B or C