Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Brentwood Biomedical Research Institute
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Healthy adult who is a tobacco dependent smoker (smokes 10-30 cigarettes per day) meeting criteria for Nicotine Dependence as defined by DSM-IV criteria
Has the desire to quit smoking
Ability to read, write, and give voluntary informed consent
An exhaled CO greater than or equal to 8 ppm during the study screening visit to verify smoking status
You may not be if
Any history of an Axis I psychiatric diagnosis other than Nicotine Dependence (including other substance abuse/dependence and mood, anxiety, and psychotic disorders)
Any current medication or any history of a medical condition that might affect the central nervous system at the time of scanning (e.g., current treatment with a psychotropic medication, or history of severe head trauma or epilepsy).
Unstable cardiovascular disease, liver disease, or renal insufficiency. Routine history and physical examination will be performed at the initial screening visit to insure that participants meet study criteria
Pregnancy (urine pregnancy tests will be obtained on all women of child-bearing potential) due to the theoretical risk of radiation exposure to the fetus. Pre-menopausal women will only be scanned during the early follicular phase (by participant report) of the menstrual cycle because hormonal levels have been shown to affect nicotine metabolism.
Caffeine dependence, as evidenced by withdrawal symptoms temporally associated with caffeine ingestion.
Clareo Health | Brain Nicotine Receptor Density & Response to Nicotine Patch
