Immune Memory After Papillomavirus Vaccination

Exclusion Criteria

• •1. Currently pregnant, breast feeding or planning a pregnancy
• •2. Underlying immunological disease, such as previously diagnosed HIV infection or history of transplantation, history of splenectomy
• •3. Use of medications with potential immunological effects such as systemic corticosteroids or chemotherapy
• •4. Prior therapy for cervical dysplasia or cervical cancer such as loop excision, laser ablation, cryotherapy or hysterectomy
• •5. Unable to comply with protocol
• •6. Severe allergic reaction (e.g., anaphylaxis) after a previous vaccine dose or to a vaccine component
• •7. An acute illness, including an oral temperature of 100.4 degrees F within three days of visit
• •other more specific exclusions may apply to one of the three cohorts