Pulmonary hypertension, peripheral edema suggesting CHF or polycythemia

Prior lung transplant, LVR, LVRS, median sternotomy, bullectomy or lobectomy

Pulmonary nodule requiring surgery

Presence of implantable electronic devices

Active respiratory infection within recent weeks

COPD exacerbation within recent weeks

Recent Myocardial infarction (MI)

Recent and unstable or life threatening arrhythmia

Malignancy treated with radiation or chemotherapy within the last 2 years

Presence or clinical diagnosis of other respiratory diseases other than COPD

Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation