Stimulant Enhancement of Well-Being Therapy for Depression

The study will have 11 visits occur over 8 weeks with study visits scheduled weekly or biweekly. Detailed Description: The study visit occurrences are as follows: 1. Week 0- Screening Visit 2. Week 1- Baseline Visit 3. Week 2- one phone visit and one clinic visit in one week 4. Week 3- one phone visit and one clinic visit in one week 5. Week 4- one visit in one week 6. Week 5- one visit in one week 7. Week 6- one visit in one week 8. Week 7- one visit in one week 9. Week 8- one visit in one week WBT description Four licensed therapists, who have been trained and certified in WBT, will provide weekly sessions of 30 to 50 minutes in duration. Therapists will follow the procedures outlined in the WBT manual. The initial sessions (weeks 0-2) will be focused on identifying and contextualizing episodes of well-being. The intermediate sessions (weeks 3-5) will be focused on modifying cognitions and behaviors, which lead to premature interruption of well-being, and optimizing cognitions and behaviors, which have been idiographically linked to enhanced well-being. Final sessions (weeks 6-8) will apply the Psychological Well-Being scales (PWB) to refine treatment according to Ryff's dimensions of well-being. Additional principles and techniques of WBT include reappraisal, mood-charting, scheduling of activities, shaping, problem-solving, and assertiveness training. Medication Schedule Participants will receive treatment with the stimulant, amphetamine/d-amphetamine, or matched placebo. Participants will start at 1 pill (placebo or 5 mg amphetamine/d-amphetamine) in the morning and 1 pill (placebo or 5 mg amphetamine/d-amphetamine) at noon. The treatment will then be flexibly adjusted up or down by a study clinician based on participant's response. Dose ranges will be 1-3 pills (placebo or 5 mg amphetamine) in the morning and 1-3 pills (placebo or 5 mg amphetamine) at noon.