Urinary 8-isoprostane is Elevated in Acute Childhood Asthma

Exclusion Criteria

• •1. Any child with documented fever within 24 hours of study entry
• •2. Any child with a known current history of tracheo- or bronchomalacia
• •3. Any child with known clinical or laboratory evidence of shock (see below)
• •4. Any child with history of documented immunodeficiency, rheumatologic disease, cystic fibrosis, or renal dysfunction (see below)
• •5. Any child with a current or recent (less than 1 year) history of tracheostomy
• •6. Any child with a known genetic abnormality
• •7. Any pregnant child
• •8. Any child with a history of autism
• •9. Any child whose parent/caregiver is unable to give informed consent