REduction of rIsk for Contrast Induced Nephropathy

Exclusion Criteria

• •1. Fail to undergo CAG/PCI or die during the procedure；
• •2. End-stage renal diseases or renal replacement；
• •3. Pre-procedural unstable renal funciton (acute increase in serum creatinine more than 0.5mg/ml in the past 24 h)；
• •4. Intravascular administration of a contrast medium within the previous 48 hours；
• •5. Allergic to contrast medium;
• •6. Pregnancy, lactation or malignant tumoror life expectancy\< 1 year;
• •7. The use of renal toxicity drugs (non-steroidal anti-inflammatory drugs, aminoglycoside drugs, cyclosporine, cisplatin etc) within 48 h before cardiac catheter surgery and the whole process of the research;
• •8. Refer to receive renal artery angiography or surgical valve replacement in patients with rheumatic heart disease； For exclusion creteria 7, patients admited and taked aspirin are included in the study.