Establish a "Taiwan Rare Disorder Tissue Bank", to Collect and Repost Biological Samples and Disease Information From Patients With Rare Disorders

Investigation Plan 1. Study Period：From 2009 to 2013 2. Study Population：Patients with rare disorders. 3. Planned Number of Subjects： 300\~500 Subjects will be included in CMU. 4. Inclusive Criteria：A patient who is clinically diagnosed as one of rare disorders notified by Department of Health or our organization. Or a patient who is diagnosed as a probable rare disorder case by physicians. 5. Exclusive Criteria：Patients whose physical or mental status is not suitable by the judgment of health professionals. Or a patient who is \<20 years old or interdictory, yet without getting the permission from his/her legal representatives. 6. Study Site： Mainly in OPD that related to rare disorders. 7. Study Materials：Blood (for plasma, DNA and cell line), a questionnaire and a chart review form. Tissue samples are acceptable as well. 8. Application of collected materials：Samples and information will be restored in appropriate manner, and researchers will be encouraged to apply them for biological studies in the field of rare disorders thereafter.