Bone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia

Exclusion Criteria

• •Poor cardiac function: left ventricular ejection fraction \<45% as determined by MUGA or ECHO.
• •Poor pulmonary function: FEV1 and FVC \<50% predicted.
• •Poor renal function
• •Positive leukocytotoxic crossmatch
• •Women of childbearing potential who currently are pregnant (Β-HCG+) or who are not practicing adequate contraception
• •Uncontrolled viral, bacterial, or fungal infections