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UNKNOWNNANCT01367964

Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH)

West syndrome (WS) is a specific type of epilepsy (or seizure disorder) that has three features: infantile spasms (type of seizure), loss of milestones, and a specific pattern on electroencephalogram ...

Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Ann & Robert H Lurie Children's Hospital of Chicago

Collaborators

Thrasher Research Fund

Hypothesis: Preemptive ACTH will halt the evolution of hypsarhythmia and improve the EEG patterns in infants with pre-hypsarhythmic EEG. Aim. To determine whether a low dose ACTH improves EEG, we will repeat EEG one month after a 2 week course of daily ACTH.

Age

0 - 1 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Infants with pre-hypsarhythmia (Type 3 EEG) between 2 months to 12 months of age.

Exclusion Criteria

•Infants with any of the following diagnoses:
•A previous history of infantile spasms;
•Known inborn error of metabolism;
•Other symptomatic epileptic encephalopathy (e.g. Ohtahara syndrome).

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 16, 2018Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment28

Start dateJul 2011

Last updatedNov 16, 2018

Condition

Locations shown

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 16, 2018Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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