Clareo Health | Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Nanjing Medical University
Nanjing University Medical College Affiliated Wuxi Second Hospital
Xuzhou Medical University
The Second Hospital of Nanjing Medical University
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
McDonald Diagnosis of Multiple Sclerosis or 2006 Diagnosis of neuromyelitis optica.
Aged 16-65 years.
Disease duration≥2years
Poor response to steroid therapy.
Written informed consent and follow the clinic trail procedure
You may not be if
Cardiac insufficiency; Renal insufficiency; hepatic insufficiency; Total bilirubin higher than 1.5 times of upper limit of normal value; AST /ALT higher than 2.5 times of upper limit of normal value.
Combined Pneumonia or other Severe systemic bacteria infection.
Severe drug allergic history or anaphylaxis to 2 or more food or medicine.
Intracranial hypertension dues to Other brain lesions (eg. Brain cancer)/
HIV+, TPPA +， patients diagnosed as HBV or HCV.
Tumor Markers +
Severe psychotic patients, cognitive dysfunction,Or can not understand or sign the Consent Form.
Coagulation disorders.
Uncontrolled hypertension after treatment，blood pressure≥180mmHg/110 mmHg.
Pregnancy.
Enrollment in other trials in the last 3 months.
Other criteria the investigator consider improper for inclusion.
