A Study of Bi-Level Positive Airway Pressure (BIPAP) Versus Non Invasive Positive Pressure Ventilation (NIPPV) for Neonatal Respiratory Failure

Inclusion Criteria

• •1. Newborn infants with birth weight \> 500 gm.
• •2. Gestational age \> 24 completed weeks.
• •3. Intention to manage the infant with non-invasive respiratory support (i.e. no endotracheal tube), where either: the infant is within the first 7 days of life and has never been intubated or has received less than 24 hours of total cumulative intubated respiratory support the infant is within the first 28 days of life, has been managed with intubated respiratory support for 24 hours or more and is a candidate for extubation followed by non-invasive respiratory support.
• •4. No known lethal congenital anomaly or genetic syndromes.
• •5. Signed parental informed consent.