Lead Sponsor

Boehringer Ingelheim

Age

19 - No limit years

Sex

ALL

Healthy Volunteers

No

•1. Patients with essential hypertension whose blood pressure is not adequately controlled by amlodipine or telmisartan monotherapy (=140/90 mmHg, = 130/80 mmHg for those with diabetes or kidney disease)
•2. Age = 19 years at enrollment
•3. Male or female patient (or legally acceptable representative) willing and able to provide written informed consent

•1. Patients with previous exposure to Twynsta
•2. Patients with hypersensitivity to the active substances, or to dihydropyridine derivatives
•3. Female patients at second and third trimesters of pregnancy
•4. Female patients with lactation
•5. Patients with biliary obstructive disorders
•6. Patients with severe hepatic impairment
•7. Patients with high grade aortic stenosis
•8. Patients with shock
•9. Patients with hereditary conditions such as intolerance with excipient of the products
•10. Current participation in other clinical trials or observational studies