Reversal of Heparin in Patients Undergoing Percutaneous Coronary Intervention (PCI)

Exclusion Criteria

• •1. The patient requires emergency surgery under conditions which prevent compliance with this protocol or which might cause unacceptable risk to the patient.
• •2. The patient requires any concomitant surgical procedures (e.g., carotid artery, CABG) during the PCI.
• •3. The patient has received any investigational drug within 30 days of study enrollment, or has had any prior exposure to PMX-60056.
• •4. The patient has any condition or abnormality which may, in the opinion of the Investigator, compromise the safety of the patient.
• •5. The patient is pregnant or breast feeding.
• •6. The patient is of childbearing potential and not under adequate contraceptive protection.
• •7. The patient has a history of clinically significant hematologic disease including heparin-induced thrombocytopenia, bleeding disorders, or platelet count \<100,000.
• •8. Severe impaired hepatic function (SGOT, SGPT \>2 x ULN).
• •9. History of AIDS, ± HIV.
• •10. History of allergy to heparin (beef or pig), protamine, or salmon.
• •11. History of chronic alcohol or drug abuse within the last one year.