Lead Sponsor

Umeå University

Collaborators

Age

All ages

Sex

ALL

Healthy Volunteers

No

•Patients with a confirmed diagnosis in accordance with the criteria proposed by the European Society of Cardiology and with NYHA III-IV symptoms. And at least one of following criteria;
•1. At least one episode of worsening heart failure that resolved with injection / infusion of diuretics or the addition of other heart failure treatment in the last 6 months and regarded optimally treated according to the responsible physician.
•2. Need for infusions-treatment.
•3. Chronic poor quality of life (VAS \< 50)
•4. Signs of cardiac cachexia (involuntary non-oedematous weight loss ≥ 6% of total body weight within the last 6-12 months)
•5. less than one year life expectancy.

•Ineligible are patients:
•1. who do not want to participate in the study;
•2. with severe communication problems;
•3. with severe dementia;
•4. with other serious disease in which heart failure is of secondary importance;
•5. with other life-threatening illness as the primary diagnosis with expected short survival;
•6. when the Primary Care Center which is responsible for patient care is geographically located from more than 30 km radius outside the hospital; and
•7. participating in another clinical trial. -

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