Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Idorsia Pharmaceuticals Ltd.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females aged 18 to 75 years (inclusive) at screening.
Body mass index (BMI) between 18 and 35 kg/m2 (inclusive) and body weight at least 50 kg at screening and prior to enrollment.
12-lead ECG without clinically relevant abnormalities measured at screening.
Clinical chemistry, hematology, coagulation, virus serology, and urinalysis test results not deviating to a clinically relevant extent from the normal range at screening.
Signed informed consent in the local language prior to any study-mandated procedure
You may not be if
Mean SBP \> 180 mmHg.
Severe, malignant, or secondary hypertension.
Episodes of hypertensive crisis or hypertensive emergency within 6 months prior to enrollment.
Previous history of fainting, collapse, syncope, orthostatic hypotension, or vasovagal reactions considered to be of clinical significance.
E6 Severe coronary artery disease indicated by myocardial infarction, percutaneous coronary intervention, or coronary artery bypass graft within the last 12 months prior to enrollment.
Angina pectoris within 6 months prior to enrollment
