* Transaminases \<= 3 x upper normal value \<= 5 x upper normal value in case of liver metastasis
Creatinine \<= 1.5mg/dL
Patients should be recovered from toxicities of previous treatment.
Written informed consent by patient or surrogates
You may not be if
Patients who had been previously treated with chemotherapy for NSCLC
Active infection requiring antibiotics treatment
Prior diagnosis of other malignancy except radically treated basal cell or squamous cell carcinoma of the skin and carcinoma in situ of the uterine cervix
Peripheral neuropathy \>= grade 2 by NCI CTCAE 4.0