Standard vs High-Dose Trivalent Inactivated Flu Vaccine in Adult Hematopoetic Stem Cell Transplant (HSCT) Recipients

Exclusion Criteria

• •History of hypersensitivity to previous influenza vaccination or hypersensitivity to eggs/egg protein
• •History of Guillain-Barre syndrome
• •Evidence of hematologic malignancy or disease relapse post-transplant (mixed chimerisms and molecular evidence of disease is permitted)
• •Non-allogeneic (e.g. autologous) hematopoietic SCT recipients
• •History of receiving 2011 - 2012 influenza vaccine
• •History of proven influenza disease after September 1, 2011.
• •Pregnant females
• •Have any condition that would, in the opinion of the site investigator, place them at an unacceptable risk of injury or render them unable to meet the requirements of the protocol
• •Have any condition that the investigator believes may interfere with successful completion of the study
• •Platelet count less than 50,000 cells/μL
• •History of known infection with HIV, Hepatitis B or Hepatitis C
• •History of known latex hypersensitivity