* Alterations of neurophysiologic regulation has been suggested in patients with major depressive disorder or bipolar disorders
* Depressive phase of bipolar disorder shows multi-faceted characteristics different from unipolar depression
* Quetiapine is an atypical antipsychotic licensed for treatment of bipolar depression
* The aim of this study is to investigate the pattern of neurophysiologic dysregulation in bipolar depression and its changes induced by quetiapine treatment
Age
18–50
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
DSM-IV bipolar disorder I or II
Depressive phase
Drug-naive or drug-free
You may not be if
Serious medical or neurological conditions
DSM-IV substance-related disorders (within 12 months prior to participation)
Mentally retarded
Clareo Health | Neurophysiologic Changes in Patients With Bipolar Depression
