Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin Lymphoma

Exclusion Criteria

• •Known HIV positive
• •Screening ALT or AST greater than 3X upper limit of normal
• •Baseline QTc greater than 500 msec
• •Current treatment with immunosuppressive agent (systemic glucocorticoid, cyclosporine, mycophenolate, azathioprine, sirolimus, Rituximab, infliximab, adalimumab)
• •Current treatment with any of the following: cisapride, ergot derivatives, amiodarone, quinidine, terfenadine, astemizole, rifampin/rifabutin, carbamazepine, phenobarbital, sildenafil, St. John's wort, azithromycin, carbamazepine, HIV anti-virals, methadone, pimozide, phenytoin, sedative hypnotics (midazolam, triazolam), HMG-CoA reductase inhibitors (lovastatin, simvastatin, atorvastatin)
• •Active malignancy requiring chemotherapy or radiation
• •Baseline creatinine of \> 2.0
• •Active infection requiring systemic anti-infective agent (excluding prophylactic antibiotics)
• •Hypersensitivity to processed bovine gelatin, chicken protein, neomycin, amphotericin B or chlortetracycline
• •Subject must not be on medications that interact with the metabolism of protease inhibitors