Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University
With
University of Washington
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Stage III-IV CKD measured by the MDRD equation with eGFR 15-60 ml/min/1.73m2;
Age 18-75 years;
BMI ≥ 25;
Life expectancy ≥ 1 year;
Ability to understand and provide informed consent.
You may not be if
Any acute inflammatory condition (including chronic infection requiring treatment, and collagen vascular disease including active gout);
Pregnancy;
Taking high-dose anti-oxidants (Vitamin E or C);
Chronic use of anti-inflammatory medication except low dose (\< 10mg/d) prednisone and aspirin (\< 100 mg/day);
Significant cardiac or vascular disease (symptomatic disease or CV event including congestive heart failure within 6 months);
Significant occlusive atherosclerotic disease or ischemic disease (on non-invasive or invasive diagnostic procedures);
Significant physical immobility or disabilities (joint replacement, muscular disorders);
Type I diabetes mellitus, or Type II requiring insulin therapy;
History of poor adherence to medical regimen;
Those subjects who have a diagnosis of atrial fibrillation or a pacemaker will be allowed in the study but will not undergo Arterial Tonometry (PWV) studies.
