Iron Indices and Intravenous Ferumoxytol: Time to Steady State

Exclusion Criteria

• •Subjects who have been enrolled in a clinical trial within the past 30 days
• •Subjects who have received IV iron within 4 weeks of the start of the study
• •Serum ferritin greater than or equal to 1200 ng/dL
• •Hemoglobin (Hb) less than 10 grams/deciliter (g/dL), or greater than 13.5 g/dL
• •Evidence of iron overload
• •Known hypersensitivity to ferumoxytol or any of its components
• •Anemia caused by conditions other than iron deficiency
• •Subjects with elective surgeries scheduled within the next 3 months
• •Subjects with elective magnetic resonance procedure scheduled during the study period
• •Subjects who have been hospitalized within the past 30 days (excluding vascular access care)
• •Subjects who have received a blood transfusion in the past 30 days
• •Subjects who are transfusion dependent
• •(Female) Subjects who are pregnant or nursing
• •Subjects with known inflammatory conditions which may affect serum ferritin
• •Subjects who are considered to be clinically unstable at the discretion of Principal Investigator (P.I.)
• •Subjects who have a clinically unstable blood pressure (BP) of systolic greater than 180 millimeters of mercury (mmHg) and/or diastolic greater than 100 mmHg (sitting, pre-dialysis)
• •Subjects with life expectancy less than 6 months
• •Subjects who refuse to sign consent