Lead Sponsor

University of Denver

Collaborators

Age

18 - 55 years

Sex

ALL

Healthy Volunteers

No

•must comprehend English well
•be 18-55 years of age
•meet enhanced DSM-IV criteria for remission of MDD, recurrent and have a history of three or more previous episodes of DSM-IV major depression in the absence of a history of mania or hypomania
•at least one of those episodes was within the past two years
•participant must be in remission and if on antidepressant medication (ADM), they must be on a stable dose with no change in type or amount for past 12 weeks or participants must be off ADM at T1 for at least the preceding 12 weeks
•have, at screening assessment, residual depressive symptoms indicated by a Beck Depression Inventory-II (BDI-II;\[72\]) score between 6-19.

•bipolar disorder
•schizophrenia or borderline personality disorder
•current suicidal thoughts and/or suicide attempt in last two months
•current anxiety disorder if it constitutes the predominant aspect of the clinical presentation and requires primary treatment not offered in the project
•substance abuse or dependence within last three months
•dementia or subnormal intellectual potential
•current obsessive-compulsive disorder
•current eating disorder
•history of previous mindfulness training or more than eight lifetime sessions of CBT
•current use of psychotherapy or counseling

Related studies

NCT06487481 · Adrenocortical Carcinoma (ACC), Recurrent Adrenocortical Carcinoma (ACC), and more

NCT05969574 · Infertility, Female, Miscarriage, and more

NCT05902169 · Glioblastoma, Recurrent Glioblastoma, and more

NCT05303467 · Glioblastoma Multiforme, Recurrent Glioblastoma

NCT06541639 · Advanced or Recurrent Solid Tumors

The Effects and Mechanisms of Mindfulness Based Cognitive Therapy (MBCT) on Depressive Symptoms and Depression Relapse