Clinical Trial of Coenzyme Q10 and Lisinopril in Muscular Dystrophies

Exclusion Criteria

• •Spine curvature greater than 30% (based on the x-ray performed at screening)
• •History of significant concomitant illness or significant impairment of renal or hepatic function
• •History of hypersensitivity to ACE inhibitors
• •History of idiopathic or hereditary angioedema or a history of angioedema with prior ACE inhibitor use
• •Use of carnitine, creatine, glutamine, or any herbal medicines (this would not include herbal teas unless they are consumed daily with intended medicinal effect) in the 3-months prior to enrollment
• •CoQ10 and/or ACE inhibitor use for a duration greater than 6 months
• •CoQ10 and/or ACE inhibitor use in the 3-months prior to enrollment
• •CoQ10 serum level of 2.5 ug/ml or higher
• •Investigator assessment of inability to comply with protocol