Age 18 years or older

Clinically confirmed viable pregnancy at the time of enrollment

Clinically determined gestational age between 8 wks, 0 days and 22 wks, 0 days

Referred or planning to undergo CVS or amniocentesis procedure due to risk of fetal aneuploidy based on protocol-specified clinical indicators

Able to provide consent for participation using language appropriate forms and consent process

MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy