Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Winthrop University Hospital
With
National Kidney Foundation, United States
Vitamin D2 is a fat soluble steroid hormone precursor which must be hydroxylated in the liver and kidney respectively to make the active form 1-25-Vitamin D. This active metabolite and related analogs have been synthesized and are frequently used in the treatment of hyperparathyroidism in patients with chronic kidney disease. However the active metabolite may not be back metabolized to the precursor forms which may have functions in other organs including the skin. Supplementation of hemodialysis patients with oral vitamin D forms would provide a source of precursors for use throughout the body.
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Hemodialysis treatment for \> 3 months
2. Subjective complaint of excessive itching
You may not be if
1. Age \< 18 years
2. Failure to provide informed consent
3. Intact PTH \< 70 pg/ml or \> 1,000 pg/ml
4. Serum phosphorus \> 7.0
5. Serum calcium (adjusted for albumin)\> 11
6. Active malignancy
7. Likelihood of imminent renal transplantation
8. Current ergocalciferol treatment
Clareo Health | A Study of Oral Ergocalciferol to Treat Pruritis in Hemodialysis Patients
