Response to Albuterol Delivered Through an Anti-static Valved Holding Chamber During Nocturnal Bronchospasm

Inclusion Criteria

• •Age 18-65 years.
• •Physician diagnosis of asthma.
• •FEV1 60-80% predicted during the day.
• •FEV1 increases ≥ 12 % and to ≥ 80% predicted after 2- 4 puffs of albuterol HFA MDI delivered by antistatic VHC.
• •No smoking in the previous year and \< 10-pack year history.
• •No history of severe asthma attacks requiring ER visit or hospitalization in the previous three months.