Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Genta Incorporated
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Confirmed diagnosis of adenocarcinoma of the stomach or esophagogastric junction
Measurable disease (revised RECIST; Version 1.1) based on computed tomography
Eastern Cooperative Oncology Group performance status 0 or 1
Treatment with only 1 prior regimen (as first-line therapy) and that regimen included a fluoropyrimidine and/or a platinum analogue
Documented disease progression within 4 months of the last dose of the 1 prior regimen
Adequate bone marrow, hepatic, and renal function, as defined in the protocol
At least 4 weeks and recovery from effects of prior surgery or other therapy, including immunotherapy, radiation therapy, or cytokine, biologic or vaccine therapy, with an approved or investigational agent
Ability to swallow an oral solid-dosage form of medication
You may not be if
Nonmeasurable disease only (revised RECIST; Version 1.1)
History or presence of brain metastasis or leptomeningeal disease
Operable gastric cancer or operable cancer of the esophagogastric junction
Uncontrolled diarrhea, defined as more than 3 loose bowel movements above the patient's usual number of bowel movements on at least 2 days within the 14 days prior to enrollment
Uncontrolled nausea or vomiting within the 14 days prior to enrollment despite the administration of standard antiemetic therapy
Known malabsorptive disorder
Significant medical disease other than cancer, as defined in the protocol
Presence of neuropathy \> Grade 1 (National Cancer Institute Common Toxicity Criteria \[NCI CTC\]; Version 4.0)
Prior treatment with a taxane or other tubulin-targeted agent (eg, indibulin) other than a vinca alkaloid
Need to continue any regularly-taken medication that is a potent inhibitor or inducer of the CYP3A pathway or P-glycoprotein activity
Clareo Health | Tesetaxel as Second-line Therapy for Patients With Advanced Gastric Cancer
