Home Mechanical Ventilation Effectiveness and Air Leaks

Inclusion Criteria

• •Patients with a restrictive pulmonary disease (slow evolution neuromuscular or thorax cage diseases, obesity or nocturnal hypoventilation) and hypercapnic chronic respiratory failure with standard criteria for NIV.
• •COPD patients who need NIV because of another reason (obesity, nocturnal hyperventilation or nocturnal hypercapnic response to oxygen).
• •PaCO2 ≥ de 50 mmHg.
• •Clinically stable (at least for one month).
• •Possibility to fit a nasal mask for NIV treatment (ultra mirage, mirage).