Pacing for Heart Failure With Preserved Ejection Fraction

Exclusion Criteria

• •Patients who have undergone cardiac surgery 60 days prior to enrollment
• •Patients who have had a myocardial infarction 90 days prior to enrollment
• •Patients with hemodynamically significant uncorrected cardiac valvular disease
• •Patients with active myocarditis and amyloidosis (if documented)
• •Patients with a permanent pacemaker
• •Patients with creatinine greater than 2 milligrams per milliliter or estimated glomerular filtration rate (eGFR) less than 30 to 50 milliliters per hour
• •Patients with permanent or chronic sustained atrial fibrillation (fibrillation lasting 7 days or more at a time)
• •Patients with a PR interval greater than 250 milliseconds
• •Patients with severe chronic obstructive pulmonary disease
• •Patients with high risk coronary artery disease
• •Patients who are or expect to become pregnant during this study
• •Patients enrolled in concurrent studies which could confound the results of this study
• •Patients with hypertrophic cardiomyopathy (obstructive or non-obstructive)
• •Patients with infiltrative disease or restrictive cardiomyopathy
• •Patients with indication for percutaneous coronary intervention (PCI) at enrollment