Lead Sponsor

Boston University

Collaborators

Age

21 - 80 years

Sex

ALL

Healthy Volunteers

No

•1. Male and Female subjects.
•2. Age range: 21-80 years old.
•3. Weight less than 115 kg.
•4. Clinically defined coronary artery disease that is clinical stable and compensated with appropriate treatment. Coronary disease (CVD) is defined by the presence of lesions on coronary angiography, history of myocardial infarction, or positive stress test.
•5. Willingness to give written informed consent and willingness and ability to understand, to participate to and to comply with the study requirements.

•1. History of nut allergy.
•2. Pregnant or lactating women. Pregnancy will be excluded by urine pregnancy test.
•3. Clinical history of other major illness including end-stage cancer, renal failure, hepatic failure, gastrointestinal disorders that may impair absorption, or other conditions that in the opinion of the principal investigator make a clinical study inappropriate.
•4. Treatment with an investigational new drug within the last 30 days.
•5. History of a psychological illness or condition such as to interfere with the subject's ability to understand the requirements of the study.
•6. Unwillingness to comply with the requirements of study including refraining from consumption of nuts and refraining from use of Vitamin E, vitamin C, and beta carotene, lipoic acid, and/or other dietary or herbal supplements during the study.

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